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Year : 2022  |  Volume : 10  |  Issue : 1  |  Page : 109-111

Endometrial clear cell carcinoma with leiomyoma and adenomyosis in a postmenopausal lady - A case report with review

Department of Pathology, Institute of Medical Sciences and SUM Hospital, S'O'A (Deemed to be) University, Bhubaneswar, Odisha, India

Correspondence Address:
Dr. Pranita Mohanty
Department of Pathology, Institute of Medical Sciences and SUM Hospital, S'O'A (Deemed to be) University, Bhubaneswa - 751 003, Odisha
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/amhs.amhs_224_21

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Endometrial cancer (EC) is the 6th most common cancer in women and endometrial clear cell carcinoma (CCC) comprised 2% of it. The association of uterine leiomyoma (UL) and adenomyosis (AM) with endometrioid variant of EC is well established, especially in postmenopausal women. Although the pathogenesis is still debatable, their presence with CCC is extremely uncommon. Moreover, the relation between CCC, AM, and UL is not yet validated because of limited data. Here, we report such a case of CCA associated with leiomyoma and AM in a 58-year-old postmenopausal Indian woman who presented with complaints of vaginal bleeding and watery discharge. She underwent hysterectomy and histopathology revealed CCC with multiple ULs and foci of AM, but there was no evidence of tumor transitioning from adenomyotic foci. This case study was aimed to evaluate if there really exists any clinicopathological correlation, tumor progression, and prognostic significance or simply this was a coexistence of all three entities.

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