Figure 4: Hieronymus Bosch's The Cure for Madness (or Folly), also known as The Stone Operation The Extraction of the Stone of Madness or The Cure of Folly, is a painting by Hieronymus Bosch, displayed in the Museo del Prado in Madrid, completed around 1494 or later. The painting depicts a surgeon, wearing a funnel hat, removing the stone of madness from a patient's head by trepanation. An assistant, a monk bearing a tankard, stands nearby. A woman with a book balanced on her head looks on. (lsink, Matthijs et al. (2016). Hieronymus Bosch: Painter and Draughtsman – Catalogue raisonné. New Haven: Yale University Press Hieronymus Bosch: Painter and Draughtsman). Reference Gross CG. A Hole in the Head: More Tales in the History of Neuroscience. Cambridge (Massachusetts): MIT Press; 2009.